欧洲杯线上买球

清华主页 - 清华新闻 - 科学研究 - 正文

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清华新闻网531日电 线粒体是细胞内最重要的细胞器之一,细胞内存在多种线粒体质量控制机制,以维持细胞内线粒体的稳态。线粒体损伤较小时可以通过线粒体融合、线粒体外膜出泡(MDV)等方式改善线粒体状态。而线粒体自噬以及线粒体蛋白酶降解途径,主要是用来清理细胞内损伤严重的线粒体。受损严重的线粒体如果不能被及时清理,则会释放大量的死亡因子,从而影响周围健康线粒体的稳态维持,并可能诱导细胞凋亡。

5月27日,清华大学生命学院俞立教授实验室在《细胞》(Cell)期刊上发表了题为“线粒体分泌,一种迁移体介导的线粒体质量控制机制(Mitocytosis, a migrasome mediated mitochondrial quality control process)”的研究论文。该论文报道了一种全新的线粒体质量控制机制——线粒体分泌(Mitocytosis),其参与调控细胞内线粒体的稳态维持。这项工作也第一次揭示了迁移体(migrasome)的细胞自主性功能。

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OUZHOUBEIXIANSHANGMAIQIU:2021NIAN05YUE31RI 14:02:28

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